Wolf Creek is an unincorporated community in Josephine County, Oregon, United States, just off Interstate 5. There are a number of creeks in Oregon named Wolf Creek, after the wolves that were once abundant in the state. Wolf Creek post office was established 1882, while a railroad station called "Almaden" was located in the same place in 1883. The station was renamed to match the post office in 1888, and in 1895 the post office was renamed to "Wolfcreek" until 1951.