Partlow is an unincorporated community in Spotsylvania County in the U.S. state of Virginia. Partlow is a small rural community located between Jefferson Davis Highway and Lake Anna. It sits at an elevation of 400 feet, and appears on the Lake Anna East U.S. Geological Survey Map. Partlow's zip code is 22534, and as of the 2000 census, it had a population of 2,083. Partlow is located 31 miles northwest of the city of Richmond, Virginia.