La Crescent is a city in Houston and Winona counties in the U.S. state of Minnesota. The population was 5,276 at the 2020 census. La Crescent is located in the northeast portion of Houston County; the northern edge of the city falls into Winona County. The city is known as the "Apple Capital of Minnesota" because John S. Harris planted apple trees here, resulting in many orchards in the present-day city.