Penne is an Italian town in the province of Pescara, in the Abruzzo region, in mid-southern Italy. According to the last census in 2014 the population was 12,451. It is one of I Borghi più belli d'Italia. Penne is today among the most important towns in the Vestini area, sitting in the hills between the Apennine Mountains and the Adriatic Sea and opening the way for the National Park of Gran Sasso and Monti della Laga through the Regional Natural Reserve "Lake of Penne".