Horry County is a county in the U.S. state of South Carolina. As of the 2010 census, its population was 289,650, making it the fifth-most populous county in South Carolina. The county seat is Conway. Horry County is the central county in the Myrtle Beach-Conway-North Myrtle Beach, SC-NC Metropolitan Statistical Area. It is located in the Pee Dee region of South Carolina, approximately 90 miles north of Charleston, South Carolina and approximately 130 miles east of the state capital, Columbia.