La Pine is a city in Deschutes County, Oregon, United States, incorporated on December 7, 2006. La Pine is part of the Bend, Oregon Metropolitan Statistical Area. The population was 2,512 people as of the 2020 Census. La Pine is in an isolated area of Central Oregon, consisting of a loose collection of homes and businesses along U.S. Highway 97 about 30 miles southwest of Bend. Several peaks of the Cascade Range are prominently visible from the community.