Ghent is a census-designated place in the town of Ghent in Columbia County, New York, United States. The population of the CDP was 477 at the 2022 survey, out of a total town population of 5,402. The community is located 11.3 miles northeast of the city of Hudson on New York Route 66. Ghent was originally the site of a Mahican Native American village known as Squampamock, Scom-pa-muck or Squampanoc.