Regis is a neighborhood in Denver. Located in North Denver, its boundaries are Harlan Street to the west, Clear Creek to the northwest, 52nd Avenue and the northern border of the Regis University campus to the north, Federal Boulevard to the east, and highway I-70 to the south. The Berkeley neighborhood is adjacent to its south end and the Chaffee Park neighborhood is adjacent to its east end. Located in the neighborhood is Regis University and the Willis Case golf course.