Pickens County is a county located on the west central border of the U.S. state of Alabama. As of the 2020 census, the population was 19,123. Its county seat is Carrollton, located in the center of the county. It is a prohibition, or dry county, although the communities of Carrollton and Aliceville voted to become wet in 2011 and 2012, respectively. Pickens County is included in the Tuscaloosa, AL Metropolitan Statistical Area