Madison County is a county located in the northeastern part of the U.S. state of Georgia. As of the 2020 census, the population was 30,120. The county seat is Danielsville. The county was created on December 5, 1811. The county's largest city is Comer with a population of 1,200. Madison County was included in the Athens–Clarke County metropolitan area, which is included in the Atlanta–Athens–Clarke County–Sandy Springs CSA.