Millesimo is a comune in the Province of Savona in the Italian region Liguria, located about 60 kilometres west of Genoa and about 25 kilometres northwest of Savona. Millesimo borders the following municipalities: Cengio, Cosseria, Murialdo, Osiglia, Pallare, Plodio, and Roccavignale. It is one of I Borghi più belli d'Italia.