The Lower East Side, sometimes abbreviated as LES and sometimes referred to as Loisaida, is a neighborhood in the southeastern part of the New York City borough of Manhattan, roughly between the Bowery and the East River from Canal to Houston streets. Traditionally an immigrant, working-class neighborhood, it began rapid gentrification in the mid-2000s, prompting the National Trust for Historic Preservation to place the neighborhood on their list of America's Most Endangered Places.