Tunuyán is a city in the west of the province of Mendoza, Argentina, located on the western shore of the Tunuyán River, 80 km south from the provincial capital Mendoza and 100 km east of the Chilean border. It has 49,132 inhabitants, and is the head town of the Tunuyán Department. Along with the Tupungato Department and the San Carlos Department it makes up the "Valle de Uco" region, which is famous in the Argentine wine industry for its important and modern vineyards and wineries.