Locust Grove is a historic home located at Charlottesville, Virginia, United States. It was built between 1840 and 1844, and is a two-story, five-bay, Georgian style brick dwelling. It has a hipped roof and end chimneys. On the front facade is a portico with coupled paneled columns. Also on the property are a contributing original kitchen and smokehouse. It was listed on the National Register of Historic Places in 1982. It is located in the Martha Jefferson Historic District.