Fuquay-Varina is a town in southern Wake County, North Carolina, United States, lying south of Holly Springs and southwest of Garner, and north of the Harnett County town of Angier and west of the unincorporated community of Willow Springs. The population was 17,937 at the 2010 census, and estimated at 36,736 as of July 2021. The hyphenated name attests to the town's history as two separate towns. Fuquay Springs and Varina merged in 1963 to create the modern town.