Pickerington is a city in Fairfield and Franklin counties in the central region of the U.S. state of Ohio. It is a suburb of Columbus. The population was 23,094 at the 2020 census. It was founded in 1815 as Jacksonville, named after Andrew Jackson. The name was changed in 1827 in honor of its founder, Abraham Pickering. As land annexation, development, and immigration into the Columbus area continues, the city of Pickerington has generally followed suit.