Greenway Plaza is a business district located along Interstate 69 within the Interstate 610 loop in southwestern Houston, Texas, 5 miles west of Downtown and 3 miles east of Uptown. The district is located immediately west of Upper Kirby, north of West University Place, and south of River Oaks. First envisioned in the late 1960s by local developer Kenneth L. Schnitzer, Greenway Plaza has evolved into one of Greater Houston's largest employment centers, with over 4.4 million square feet of office space on a 52-acre campus.