Humboldt County is a county in the U.S. state of Nevada. As of the 2020 Census, the population was 17,285. It is a largely rural county that is sparsely populated with the only major city being Winnemucca which has a population of 8,431. Humboldt County comprises the Winnemucca, NV Micropolitan Statistical Area and serves as an important crossroads in the national transportation network.