Ruby is an incorporated town in central western Alaska, situated on the south bank of the Yukon River at the northwesternmost tip of the Nowitna National Wildlife Refuge. It is accessible only by boat or air. A formerly sizeable gold-mining and lumbering town servicing the region, at the 2010 census the population was just 166, with only a general store and post office remaining as businesses, down from 188 in 2000. It is served by Ruby Airport.