Santo Stefano Lodigiano is a comune in the Province of Lodi in the Italian region Lombardy, located about 60 kilometres southeast of Milan and about 25 kilometres southeast of Lodi. Santo Stefano Lodigiano borders the following municipalities: Maleo, Corno Giovine, Corno Giovine, Fombio, San Fiorano, Caselle Landi, Piacenza, Piacenza, San Rocco al Porto. The municipality is home to a Baby& Toy Museum with more than 1,700 items.