Menifee is a city in Riverside County, California, United States, and is part of the Inland Empire. Named after a local miner, Luther Menifee Wilson, it was settled in the 19th century, and incorporated as a city in 2008. Since then, Menifee has become one of the fastest growing cities in California and the United States. The city is centrally located in Southern California in the Menifee Valley. It is almost 15 miles north of Temecula and just north of Murrieta.