Glen Flora is an unincorporated community in Wharton County, Texas, United States. According to the Handbook of Texas, the community had an estimated population of 210 in 2000. It is located within the Greater Houston metropolitan area. On November 21, 1992, an F1 tornado destroyed several barns northeast of the community. Four homes were damaged by another tornado on November 23, 2004. Glen Flora has a post office with the zip code 77443.