Iquitos is the capital city of Peru's Maynas Province and Loreto Region. It is the largest metropolis in the Peruvian Amazon, east of the Andes, as well as the ninth-most populous city in Peru. Iquitos is the largest city in the world that cannot be reached by road that is not on an island; it is only accessible by river and air. It is known as the "capital of the Peruvian Amazon". The city is located in the Great Plains of the Amazon Basin, fed by the Amazon, Nanay, and Itaya rivers.