Pauline is an unincorporated community and census-designated place in Spartanburg County, South Carolina, United States. It was first listed as a CDP in the 2020 census with a population of 209.Until the 1890s, Pauline was known as Stribling. The community took the name "Pauline" when they were to name a post office and the name "Stribling" was already taken; "Pauline" was the first name of the postmaster's daughter at the time. Pauline has a post office with the zip code 29374.