The Cliffs Valley is a resort community and census-designated place in Greenville County, South Carolina, United States. It was first listed as a CDP prior to the 2020 census with a population of 736. The CDP is on the northern edge of Greenville County, extending north to the North Carolina border. U.S. Route 25 forms the western edge of the CDP; the highway leads south 21 miles to Greenville and north 16 miles to Hendersonville, North Carolina.