Paniai Regency is one of the regencies in Central Papua Province of Indonesia. It is named after the Paniai Lakes. It covers an area of 6,525.25 km2, and had a population of 153,432 at the 2010 Census and 220,410 at the 2020 Census; the official estimate as of mid-2022 was 227,254- comprising 124,260 males and 102,994 females. The administrative centre is the town of Enarotali, in East Paniai.