Chorlton-on-Medlock is an inner city area of Manchester, in the county of Greater Manchester, England. Historically in Lancashire, Chorlton-on-Medlock is bordered to the north by the River Medlock, which runs immediately south of Manchester city centre. Its other borders roughly correspond to Stockport Road, Hathersage Road, Moss Lane East and Boundary Lane. Neighbouring districts are Hulme to the west, Ardwick to the east and Victoria Park, Rusholme and Moss Side to the south.