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The Mayo Hotel is a historic building located in downtown Tulsa in Oklahoma, US, at 115 West 5th Street. This Chicago School (Sullivanesque) building was built in 1925. It was designed by the architect George Winkler and financed by John D. and Cass A. Mayo. The base of two-story Doric columns supports fourteen floors marked with false terracotta balconies, and a two-story crown of stone and a dentiled cornice It was listed on the National Register of Historic Places in 1980.
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