Platteville is the largest city in Grant County, Wisconsin, United States. The population was 11,836 at the 2020 census. Platteville is located atop the greater Platte River valley in the southern Driftless Region of Wisconsin, an area known for its karst topography and rolling hills. It is home to the University of Wisconsin–Platteville. It is the principal city of the Platteville micropolitan statistical area, which has an estimated population of 51,938.