Salesópolis is a municipality in the state of São Paulo in Brazil. It is part of the Metropolitan Region of São Paulo. The population is 17,252 in an area of 424.997 km². Salesópolis sits at an elevation of 850 metres. It is noted for being the source of the Tietê River. Salesópolis was founded in the 19th century as São José do Paraitinga, and later became the parish of Santana de Mogi das Cruzes in 1838.