Lomello is a comune in the Province of Pavia in the Italian region Lombardy, located about 50 km southwest of Milan and about 30 km west of Pavia, on the right bank of the Agogna. It gives its name to the surrounding area, the Lomellina. Lomello borders the following municipalities: Ferrera Erbognone, Galliavola, Mede, Ottobiano, San Giorgio di Lomellina, Semiana, Velezzo Lomellina, Villa Biscossi.