Palenville is a hamlet and census-designated place in Greene County, New York, United States. The population was 1,002 at the 2020 census. Palenville is in the southwestern part of the town of Catskill, located at the junction of Routes 23A and 32A. It lies at the foot of Kaaterskill Clove, at the base of the Catskill Mountains. Kaaterskill Creek, exiting the Clove, runs through the town, and was spanned by a swinging footbridge, destroyed during Tropical Storm Irene.