The Shire of Millmerran was a local government area in the Darling Downs region of Queensland, Australia, about 80 kilometres southwest of the regional city of Toowoomba. The shire covered an area of 4,520.8 square kilometres, and existed as a local government entity from 1913 until 2008, when it amalgamated with several other councils in the Toowoomba area to become the Toowoomba Region.