Jamacha is a neighborhood in the southeastern area of San Diego, California. It is generally bounded by the city of Lemon Grove to the north, unincorporated La Presa to the east, Imperial Avenue and Encanto to the west, and Skyline and Lomita Village to the south. Major thoroughfares include Lisbon Street, Jamacha Road, and Woodrow Avenue. The neighborhood is part of the Skyline-Paradise Hills Community Planning Area.