Guissona is a town and municipality located in the north of the comarca of Segarra, in the province of Lleida, Catalonia, Spain. With 6,862 inhabitants Guissona is the principal municipality in the northern half of Segarra and the second most populated in the county after Cervera. In addition to the populated place of Guissona, the municipality integrates the smaller place of Guarda-si-venes.