Itasca is a village in DuPage County, Illinois, United States. Per the 2020 Census, the population was 9,543. Located approximately 25 miles northwest of downtown Chicago, Itasca is close to O'Hare International Airport, major expressways and rail transportation. Itasca is home to a country club, a resort and shares a border with Medinah's legendary golf course. BusinessWeek rated Itasca as the Best Affordable Suburb in the state of Illinois.