Sequoyah County is a county located in the U.S. state of Oklahoma. As of the 2020 census, the population was 39,281. The county seat is Sallisaw. Sequoyah County was created in 1907 when Oklahoma became a state. It was named after Sequoyah, who created the Cherokee syllabary and its written language. Sequoyah County is part of the Fort Smith, AR-OK metropolitan statistical area.