Smithfield is a town in Isle of Wight County, in the South Hampton Roads subregion of the Hampton Roads region of Virginia in the United States. The population was 8,533 at the 2020 census. The town is most famous for the curing and production of the Smithfield ham. The Virginia General Assembly passed a statute defining "Smithfield ham" by law in 1926, with one of the requirements that it be processed within the town limits.