Tsaile is a census-designated place in Apache County, Arizona, United States, on the Navajo Nation. The population was 1,205 at the 2010 census. Tsaile is the home of the main campus of Diné College, a tribally controlled community college. It has seven other campuses across the Navajo Nation. Tsaile Public School is located in Tsaile. Students attend Chinle High School in Chinle, Arizona, for high school, which is about 25 miles away via Navajo Route 64.