San Antonio, or unofficially "San Ann" or "San An" as the locals call it, is a city in Pasco County, Florida, United States. It is a suburban city included in the Tampa-St. Petersburg-Clearwater, Florida Metropolitan Statistical Area, much more commonly known as the Tampa Bay Area. It lies within Florida's 12th congressional district. The population was 1,297 at the 2020 census. It was established as a Catholic colony by Judge Edmund F. Dunne.