Upper Red Hook is a hamlet and census-designated place in the town of Red Hook in Dutchess County, New York, United States. It was first listed as a CDP prior to the 2020 census. The community is in northwestern Dutchess County, in the northeastern part of the town of Red Hook. U.S. Route 9 passes through the CDP, leading north 18 miles to Hudson and southwest through Red Hook village 8 miles to Rhinebeck.