Highbridge is a residential neighborhood geographically located in the central-west section of the Bronx, New York City. Its boundaries, starting from the north and moving clockwise, are the Cross-Bronx Expressway to the north, Jerome Avenue to the east, Macombs Dam Bridge to the south, and the Harlem River to the west. Ogden Avenue is the primary thoroughfare through Highbridge. The neighborhood is part of Bronx Community Board 4, and its ZIP Code is 10452.