Elk City is a city in Beckham County, Oklahoma, United States. The population was 11,561 at the time of the 2020 census, a slight decrease from the 11,693 figure of the 2010 census. Elk City is located on Interstate 40 and Historic U.S. Route 66 in western Oklahoma, approximately 110 miles west of Oklahoma City and 150 miles east of Amarillo, Texas.