Alpine is a city in and the county seat of Brewster County, Texas, United States. The population was 6,035 at the 2020 census. The town has an elevation of 4,462 feet, and the surrounding mountain peaks are over 1 mile above sea level. A university, hospital, library, and retail make Alpine the center of the sprawling 12,000 square miles but wide open Big Bend area including Brewster, Presidio, and Jeff Davis counties.