Avondale is a census-designated place and post office in and governed by Pueblo County, Colorado, United States. The CDP is a part of the Pueblo, CO Metropolitan Statistical Area. The Avondale post office has the ZIP Code 81022. At the United States Census 2020, the population of the Avondale CDP was 594, while the population of the 81022 ZIP Code Tabulation Area was 1,624 including adjacent areas.