Jefferson is a village in and the county seat of Ashtabula County, Ohio, United States. The population was 3,226 at the 2020 census. It is part of the Ashtabula micropolitan area, 50 miles northeast of Cleveland. Modern-day Jefferson sports the world's only perambulator museum and a historical complex including several restored 19th-century buildings. Joshua Giddings' law office has also been restored as a museum.