Mirante do Paranapanema is a city in the western part of the state of São Paulo, in Brazil. It is part of the microregion of Presidente Prudente. The population is 18,338 in an area of 1239 km2. The altitude is 448 m. It is situated near the Paranapanema River, which forms the border with the state of Paraná here. The municipality contains part of the 246,800 hectares Great Pontal Reserve, created in 1942.