Sabula is a city in Jackson County, Iowa, United States. The population was 506 at the 2020 census. Sabula is the site of Iowa's only island city. The island has a beach and a campground, as well as a harbor with boat docks and storage sheds to store boats during the winter. Sabula is the northern terminus of U.S. Route 67, a 1,560 mile long north–south highway in the Central United States. The southern terminus of the route is at the United States–Mexico border in Presidio, Texas.