Ripley is a census-designated place in the town of Ripley in Chautauqua County, New York, United States. As of the 2010 census, the population of the CDP was 872, out of a total town population of 2,415. Ripley is located on U.S. Route 20 and Interstate 90 in the northeast corner of the town. Ripley is a few miles east of the Pennsylvania border.