Syracuse is a town in Turkey Creek Township, Kosciusko County, in the U.S. state of Indiana. The population was 3,079 at the 2020 census. Syracuse is the location of Lake Syracuse and the nearby, larger Lake Wawasee, in addition to several other lakes in the region. The National Weather Service operates a Weather Forecast Office South of town, toward North Webster. It serves Northern Indiana, Northwestern Ohio and Southwestern Michigan.